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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRN2
All Species:
23.03
Human Site:
S790
Identified Species:
36.19
UniProt:
Q9H0D6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0D6
NP_036387.2
950
108582
S790
P
S
D
W
E
K
S
S
N
G
R
Q
W
K
P
Chimpanzee
Pan troglodytes
XP_514546
950
108522
S790
P
S
D
W
E
K
S
S
N
G
R
Q
W
K
P
Rhesus Macaque
Macaca mulatta
XP_001094734
961
109718
S801
P
S
D
W
E
K
S
S
N
G
R
Q
W
K
P
Dog
Lupus familis
XP_534324
950
108331
S790
P
S
D
W
E
K
S
S
N
G
R
Q
W
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBR1
951
108669
S790
P
G
D
W
E
K
S
S
N
G
R
Q
W
K
P
Rat
Rattus norvegicus
NP_001102066
561
63850
H430
A
A
F
R
T
L
G
H
V
I
P
R
G
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505862
950
108030
S790
P
G
D
W
E
K
S
S
N
G
R
Q
W
R
P
Chicken
Gallus gallus
Q5ZIP4
949
108524
N789
P
G
D
W
E
K
T
N
N
D
G
R
P
W
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM71
908
103942
Q762
P
Q
V
L
P
N
E
Q
S
G
N
K
H
R
P
Honey Bee
Apis mellifera
XP_392371
860
99367
T723
C
I
D
G
M
R
G
T
V
L
L
T
D
D
C
Nematode Worm
Caenorhab. elegans
Q9U299
975
110109
R818
P
D
D
W
N
D
R
R
D
G
R
Y
Q
P
Q
Sea Urchin
Strong. purpuratus
XP_795068
1073
120270
N783
P
E
D
F
L
N
A
N
G
Y
R
G
G
R
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FQ03
1020
116807
N844
N
N
H
G
M
H
N
N
Q
G
R
Q
N
P
P
Baker's Yeast
Sacchar. cerevisiae
Q02792
1006
115915
E869
L
N
G
F
I
P
S
E
P
V
L
T
A
Y
D
Red Bread Mold
Neurospora crassa
Q8WZX5
1072
118291
R867
I
L
K
G
K
A
S
R
S
G
R
S
Y
G
G
Conservation
Percent
Protein Identity:
100
99.7
97.6
98
N.A.
96
56.2
N.A.
91.1
82.9
N.A.
N.A.
N.A.
51.2
54
50.5
52.5
Protein Similarity:
100
99.8
98
99
N.A.
97
57.6
N.A.
95.4
90.5
N.A.
N.A.
N.A.
63.2
66.5
63.7
63.4
P-Site Identity:
100
100
100
100
N.A.
93.3
0
N.A.
86.6
40
N.A.
N.A.
N.A.
20
6.6
33.3
20
P-Site Similarity:
100
100
100
100
N.A.
93.3
13.3
N.A.
93.3
60
N.A.
N.A.
N.A.
40
20
40
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.6
40.5
40.8
Protein Similarity:
N.A.
N.A.
N.A.
58
57.4
56.1
P-Site Identity:
N.A.
N.A.
N.A.
26.6
6.6
20
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
20
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
0
7
7
0
0
0
0
0
7
0
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
0
7
67
0
0
7
0
0
7
7
0
0
7
7
7
% D
% Glu:
0
7
0
0
47
0
7
7
0
0
0
0
0
0
0
% E
% Phe:
0
0
7
14
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
20
7
20
0
0
14
0
7
67
7
7
14
7
20
% G
% His:
0
0
7
0
0
7
0
7
0
0
0
0
7
0
0
% H
% Ile:
7
7
0
0
7
0
0
0
0
7
0
0
0
0
0
% I
% Lys:
0
0
7
0
7
47
0
0
0
0
0
7
0
34
0
% K
% Leu:
7
7
0
7
7
7
0
0
0
7
14
0
0
0
0
% L
% Met:
0
0
0
0
14
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
14
0
0
7
14
7
20
47
0
7
0
7
0
0
% N
% Pro:
67
0
0
0
7
7
0
0
7
0
7
0
7
14
54
% P
% Gln:
0
7
0
0
0
0
0
7
7
0
0
47
7
0
7
% Q
% Arg:
0
0
0
7
0
7
7
14
0
0
67
14
0
20
7
% R
% Ser:
0
27
0
0
0
0
54
40
14
0
0
7
0
7
0
% S
% Thr:
0
0
0
0
7
0
7
7
0
0
0
14
0
0
0
% T
% Val:
0
0
7
0
0
0
0
0
14
7
0
0
0
0
0
% V
% Trp:
0
0
0
54
0
0
0
0
0
0
0
0
40
7
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
7
7
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _